Kate Rawlinson

Assistant Scientist

Kate Rawlinson headshot
Contact Information
Education
Ph.D. Marine Biology, University College Cork
M.Sc. Advanced Methods in Taxonomy and Biodiversity, Imperial College and the NHM, London
B.Sc. Biology with French, St. Andrews University
MBL Affiliation
Bay Paul Center
Research Area
Developmental Biology
Genomics
Imaging
Models of Human Disease
Neuroscience
Lab Website
Rawlinson Lab

The research of my lab focuses on the development, neurobiology and biological rhythms of parasitic helminths that impact human health and interests. We are currently working on the sensory biology and biological rhythms of the human blood fluke Schistosoma mansoni to understand infection and host-parasite interactions.

Daily rhythms in gene expression of the human parasite Schistosoma mansoni.
Venom-allergen-like 12 transcripts reach the the body wall musculature and into the tubercles of the dorsal tegument of male Schistosoma mansoni. They show daily rhythms in abundance and the protein is predicted to interact with the host.
Venom-allergen-like 12 transcripts reach the the body wall musculature and into the tubercles of the dorsal tegument of male Schistosoma mansoni. They show daily rhythms in abundance and the protein is predicted to interact with the host.
Daily rhythms in gene expression of the human parasite Schistosoma mansoni. 
3D reconstruction of part of a ciliary phaosome , a light sensitive, extra-ocular cell in a marine flatworm (cilia [pink], basal bodies [yellow]).
3D reconstruction of part of a ciliary phaosome, a light sensitive, extra-ocular cell in a marine flatworm (cilia [pink], basal bodies [yellow]).

 

News and Research Highlights
Kate Rawlinson works with
Tess Attenborough
Tess Attenborough
Dr and Bioinformatician
University of Glasgow
Matt Berriman
Matt Berriman
Professor
University of Glasgow
Gabriel Rinaldi
Gabriel Rinaldi
Associate Professor
University of Oxford
Karl Hoffmann
Karl Hoffmann
Professor
Aberystwyth University
Jessica Goodheart
Jessica Goodheart
Assistant Professor
American Museum of Natural History
Selected Publications

Attenborough T§, Rawlinson KA§*, Diaz Soria CL, Ambridge K, Sankaranarayanan G, Graham J, Cotton JA, Doyle SR, Rinaldi G, Berriman M*. A single-cell atlas of the miracidium larva of the human blood fluke Schistosoma mansoni: cell types, developmental pathways and tissue architecture. eLife13:RP95628 (2024) https://doi.org/10.7554/eLife.95628.1

Diaz Soria CL, Attenborough T, Lu Z, Graham J, Hall C, Thompson S, Andrews TGR, Rawlinson KA, Berriman M, Rinaldi G. Single cell transcriptomics of the human parasite Schistosoma mansoni first intra-molluscan stage reveals tentative tegumental and stem cell regulators. Sci Rep 14, 5974 (2024) https://doi.org/10.1038/s41598-024-55790-3

Rawlinson KA*, Reid A, Lu Z, Driguez P, Wawer A, Coghlan A, Sankaranarayanan G, Buddenborg SK, Diaz Soria CL, McCarthy C, Holroyd N, Sanders M, Wilcockson D, Hoffmann K, Collins J, Rinaldi G, Berriman M* (2021) Daily rhythms in gene expression of the human parasite Schistosoma mansoni. BMC Biology 19, 255. doi.org/10.1186/s12915-021-01189-9 

Lu Z, Sankaranarayanan G, Rawlinson KA, Offord V, Brindley PJ, Berriman M and Rinaldi G (2021) The transcriptome of Schistosoma mansoni developing eggs reveals key mediators in pathogenesis and life cycle propagation. Front. Trop. Dis.2:713123. doi: 10.3389/fitd.2021.713123

Diaz Soria, C.L., Lee, J., Chong, T. Tracey A, Young MD, Andrews T, Hall Cm Ng BL, Rawlinson KA, Doyle SR, Leonard S, Lu Z, Bennett HM, Rinaldi G, Newmark PA, Berriman M (2020) Single-cell atlas of the first intra-mammalian developmental stage of the human parasite Schistosoma mansoni. Nat Commun 11, 6411 (2020). doi.org/10.1038/s41467-020-20092-5

Rawlinson KA, Lapraz F, Ballister ER, Terasaki M, Rodgers J, McDowell RJ, Girstmair J, Criswell KE, Boldogkoi M, Simpson F, Goulding D, Cormie C, Hall BK,  Lucas RJ, Telford MJ (2019). Extraocular, rod-like photoreceptors in a flatworm express xenopsin photopigment. eLife. doi:10.7554/eLife.45465

Barton JA, Hutson, KS, Bourne DG, Humphrey C, Dybala C, Rawlinson KA (2019). The life cycle of the Acropora-coral eating flatworm (AEFW), Prosthiostomum acroporae; the influence of temperature and management guidelines. Frontiers in Marine Science. 6:524. doi: 10.3389/fmars.2019.00524

Mouahid G, Rognon A, de Carvalho AR, Driguez P, Geyer K, Karinshak S, Luviano N, Mann V, Quack T, Rawlinson KA, Wendt G, Grunau C,  Moné H (2018). Transplantation of schistosome sporocysts between host snails: a video guide. Wellcome Open Res. 3:3.

Egger B, Lapraz F, Tomiczek B, Müller S, Dessimoz C, Girstmair J, Škunca N, Rawlinson KA, Cameron C, Beli E, Todaro MA, Gammoudi M, Noreña C, Telford MJ (2015). A transcriptomic-phylogenomic analysis of the evolutionary relationships of flatworms. Curr. Biol. 25: 1-7.

​ Rawlinson KA (2014) The diversity, development and evolution of polyclad flatworm larvae. BMC EvoDevo 5: 9.

Lapraz F, Rawlinson KA, Girstmair J, Tomiczek B, Berger J, Jékely G, Telford M, Egger B (2013) Put a tiger in your tank: the polyclad flatworm Maritigrella crozieri as a proposed model for evo-devo. BMC EvoDevo 4: 29 (Highly accessed).

Rawlinson KA and Stella JS (2012) Discovery of the corallivorous polyclad flatworm, Amakusaplana acroporae, on the Great Barrier Reef, Australia – the first report from the wild. PLoS ONE 7: e42240.

Rawlinson KA, Gillis JA, Billings RE, Borneman EH (2011) Taxonomy and life history of the Acropora-eating polyclad flatworm: Amakusaplana acroporae nov. sp. (Polycladida, Prosthiostomidae). Coral Reefs 30: 693-705.

Rawlinson KA (2010) Embryonic and post-embryonic development of the polyclad flatworm Maritigrella crozieri; implications for the evolution of spiralian life history traits. Front. Zool. 7: 12.

Rawlinson KA (2008) Biodiversity of coastal polyclad flatworm assemblages in the wider Caribbean. Mar. Biol. 153: 769-778.

Rawlinson KA, Davenport J and Barnes DKA (2004) Diurnal vertical migration strategies with respect to advection and stratification in a semi-enclosed lough: a comparison of mero- and holozooplankton. Mar. Biol. 144: 935-946.