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An intensive six-week laboratory and lecture course for advanced
graduate students, postdoctoral fellows, and more senior researchers
who seek a broad and balanced view of the modern issues of
developmental biology. Limited to 24 students.
The integrated lectures and laboratories provide a comprehensive
coverage of the paradigms, problems, and technologies of modern
developmental biology, cast within a framework of metazoan evolution.
Students are exposed to a wide variety of embryonic systems, including
intensively studied genetic model systems ( e.g. C. elegans
, Drosophila , zebrafish mouse) and
others with well-established experimental attributes ( e.g.
chick, sea urchins, frogs, ascidians). In addition,
students will be introduced to a wide range of emerging systems,
including locally available marine organisms, that help fill in the
evolutionary history of animal diversity ( e.g. cnidarians,
nemerteans, planaria, crustaceans, mollusks, and annelids) and that are
becoming established as experimental systems in their own right. This
broad coverage of metazoan phylogeny allows for the analyses of the
developmental strategies that drive evolutionary change. Analytical and
experimental techniques used to explore invertebrate and vertebrate
development include embryological manipulation (e.g. cell ablation,
tissue grafting), molecular genetic ( e.g. RNAi,
electroporation) and cell biology approaches ( e.g. analysis
of cell lineage and migratory behaviour), and microscopic and imaging
technologies (e.g. confocal and 3-D time lapse), using state-of-the-art
instrumentation and methodology. Conceptual topics include cell
specification and differentiation, pattern formation, embryonic axis
formation, morphogenesis, intercellular signaling, transcriptional
regulation, organogenesis, and modern comparative embryology.
2011 Faculty and Lecturers:
Sharon Amacher, University
of California, Berkeley
Bruce Appel, University of Colorado
Denver
Clare Baker, University of Cambridge
Richard Behringer, MD Anderson Cancer
Center
Celeste Berg, University of Washington
Andres Collazo, House Ear Institute
Gerald Crabtree, Stanford University
David Fitch, New York University
Thomas Gregor, Princeton University
Iswar Hariharan, University of
California, Berkeley
Jonathan Henry, Univerisity of Illinois
Raymond Keller, University of Virginia
Nicole King, University of California,
Berkeley
Thomas Lecuit, CNRS
Amy Maddox, University of Montreal
Paul Maddox, University of Montreal
Mark Martindale, University of Hawaii
David McClay, Duke University
Victoria Prince, University of
Chicago
Matthew Ronshaugen, University of
Manchester
Janet Rossant, The Hospital for Sick
Children
Joel Rothman, University of
California, Santa Barbara
Alejandro Sanchez Alvarado, University
of Utah Medical School
Elaine Seaver, University of Hawaii
Michael Shapiro, University of Utah
David Sherwood, Duke University
Lori Sussel, Columbia University
Billie Swalla, University of
Washington
Paul Trainor, Stowers Institute for
Medical Research
John Wallingford, University of
Texas at Austin
Robert Zeller, San Diego State
University
This course is supported with funds provided by:
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